Alpha-hydroxy acids: Consideration of the biological effects and possible role in photocarcinogenesis

Authors

P.C. Howard
II R.L. Sams
D.A. Dennis
W.G. Wamer

Abstract

The U.S. Food and Drug Administration nominated topically applied alpha-hydroxy acids to the U.S. National Toxicology Program for toxicological studies. The alpha-hydroxy acids are present at significant concentrations in many cosmetic products and are marketed as products to correct photoaging of skin. In this paper, we review the current knowledge concerning the effect of topical treatment of mice with creams containing alpha-hydroxy acids and the effect of ultraviolet radiation on treated and untreated mouse skin.

Recommended Citation

Howard, P.C.; Sams, II R.L.; Dennis, D.A.; and Wamer, W.G. (2002) "Alpha-hydroxy acids: Consideration of the biological effects and possible role in photocarcinogenesis," Journal of Food and Drug Analysis: Vol. 10 : Iss. 4 , Article 6.
Available at: https://doi.org/10.38212/2224-6614.2741

Fulltext URL

http://www.fda.gov.tw/tc/includes/GetFile.ashx?id=f636694335675484097