The potential role of phenolic compounds on modulating gut microbiota in obesity

Authors

Gow-Chin Yen, Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, TaiwanFollow
Hsin-Lin Cheng, Department of Nutrition, Chung Shan Medical University, Taichung, TaiwanFollow
Li-Yu Lin, Institute of Medicine, Chung Shan Medical University, Taichung, TaiwanFollow
Shiuan-Chih Chen, Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
Chin Lin Hsu, Department of Nutrition, Chung Shan Medical University, Taichung, TaiwanFollow

Keywords

Obesity, Gut microbiota, Phenolic compounds

Abstract

Obesity is a rising public health issue and challenge which is tightly correlated with socio-economic development paralleled with increased energy intake and sedentary behavior that subsequently cause adipose tissue accumulation. Physiological and metabolic status changes during obesity development have been suggested with low grade inflammation of gastrointestinal tract. The gut microbiota plays an essential role in regulating whole body energy metabolism and also lipid accumulation, and immunity of host. However, the detail mechanism of which the gut microbiota composition influence obesity development in humans still need deeper investigation owing to the complex pathophysiology of such disease. Recently, the consumption of phenols-rich food has been showed to have physiological function that attribute to improve gut microbiota and benefit body weight management. Here, we review the current knowledge regarding phenolic compounds that regulate the development of obesity and the importance of the axis that link dietary-induced gut microbiota change and metabolic health of host. We also discuss dietary intervention reshaping gut bacterial community to modulate obesity.

Abstract Image

Recommended Citation

Yen, Gow-Chin; Cheng, Hsin-Lin; Lin, Li-Yu; Chen, Shiuan-Chih; and Hsu, Chin Lin (2020) "The potential role of phenolic compounds on modulating gut microbiota in obesity," Journal of Food and Drug Analysis: Vol. 28 : Iss. 2 , Article 1.
Available at: https://doi.org/10.38212/2224-6614.1054

Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Publisher Note

Due to printer error, this article was previously made available with incorrect page numbers. The article has been repaginated and the article is now available with the correct page numbers for volume 28, issue 2 195-205.