Simultaneous determination of 24 congeners of 2- and 3‑monochloropropanediol esters and 7 congeners of glycidyl esters using direct multi-residue analytical LC-MS/MS methods in various food matrices

Ching-Chang Lee, Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
Bo-Lun Lin, Department of Food Safety/Hygiene and Risk Management, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
Yi-Wen Huang, Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
Ning-Syuan Hsu, Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
Wei-Hsiang Chang, Research Centre of Environmental Trace Toxic Substances, College of Medicine, National Cheng Kung University, Tainan 704, TaiwanFollow

Keywords

Food matrix, Glycidyl ester, LC−MS/MS, 2-MCPD ester, 3-MCPD ester

Abstract

Glycidyl esters (GEs) and 2- and 3-monochloropropanediol esters (MCPDEs) are emerging process-generated food contaminants known as possible carcinogens. Herein, a direct method is developed and validated for the first time to simultaneously quantify seven GEs and twenty-four MCPDE congeners of processed foods using liquid chromatography-tandem mass spectrometry in a single sequence without ester cleavage or derivatisation, thereby allowing for the simultaneous analysis of numerous food matrices with high accuracy and precision. Our results show levels of GEs varying from

Abstract Image

Recommended Citation

Lee, Ching-Chang; Lin, Bo-Lun; Huang, Yi-Wen; Hsu, Ning-Syuan; and Chang, Wei-Hsiang (2023) "Simultaneous determination of 24 congeners of 2- and 3‑monochloropropanediol esters and 7 congeners of glycidyl esters using direct multi-residue analytical LC-MS/MS methods in various food matrices," Journal of Food and Drug Analysis: Vol. 31 : Iss. 1 , Article 4.
Available at: https://doi.org/10.38212/2224-6614.3442