Three-dimensional strategies in the quantitative resolution of kinetic UV absorbance measurements for monitoring the oxidation of quercetin by oxidant agents and analyzing dietary supplement product

Authors

Erdal DİNÇ, Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06560 Yenimahalle, Ankara, TurkeyFollow
Asiye ÜÇER, Department of Analytical Chemistry, Faculty of Pharmacy, Ankara Yıldırım Beyazıt University, 06010 Etlik, Keçiören, Ankara, TurkeyFollow
Nazangül ÜNAL, Department of Pharmacy Services, Eşme Vocational School, Uşak University Uşak, TurkeyFollow

Keywords

Chemometric strategies, Dietary supplement product, Kinetic UV absorbance, PARAFAC, Quercetin, UPLC

Abstract

Three-dimensional strategies involving the application of parallel factor analysis (PARAFAC) to the kinetic UV absorbance measurements were elaborated to monitor the oxidation of quercetin with oxidant agents (K₂Cr₂O₇ and KIO₃) and to quantify analyte in a dietary supplement product. Loadings (spectral, kinetic and concentration profiles) were obtained by the PARAFAC deconvolution. Spectral identification, kinetics and quantification of the relevant analyte in the presence of interferent(s) were performed. The elaborated chemometric strategies were carefully validated to demonstrate the capability of the method. Assay results of the PARAFAC strategies were statistically compared to that of the newly developed UPLC method.

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Recommended Citation

DİNÇ, Erdal; ÜÇER, Asiye; and ÜNAL, Nazangül (2023) "Three-dimensional strategies in the quantitative resolution of kinetic UV absorbance measurements for monitoring the oxidation of quercetin by oxidant agents and analyzing dietary supplement product," Journal of Food and Drug Analysis: Vol. 31 : Iss. 2 , Article 10.
Available at: https://doi.org/10.38212/2224-6614.3455

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